Stability Indicating Method Development and Validation of Finasteride by High-Performance Thin-Layer Chromatography Studies
نویسندگان
چکیده
منابع مشابه
Development and Validation of a Stability-Indicating High Performance Thin Layer Chromatography (HPTLC) Method for estimation of Canagliflozin in bulk and Pharmaceutical Dosage Form
Article history: Received on: 30/01/2016 Revised on: 13/03/2016 Accepted on: 06/04/2016 Available online: 28/05/2016 The objective of the study was to develop and validate simple, authentic and stability indicating high performance thin-layer chromatographic method for determination of Canagliflozin in bulk and pharmaceutical formulations as per ICHQ2 R1 Guidelines. HPTLC aluminium plates Preco...
متن کاملDevelopment and validation of stability indicating method for the determination of exemestane by reverse phase high performance liquid chromatography.
Exemestane is an aromatase inhibitor used in the treatment of breast cancer. A selective stability-indicating reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed which can separate and accurately quantitate low levels of exemestane. The stability-indicating capability of the method was demonstrated by adequate separation of exemestane and all the degradatio...
متن کاملStability Indicating HPLC Method Development and Validation
High performance liquid chromatography (HPLC) is an integral analytical tool in assessing drug product stability. HPLC methods should be able to separate, detect, and quantify the various drug-related degradants that can form on storage or manufacturing, plus detect and quantify any drug-related impurities that may be introduced during synthesis. Forced degradation studies of new chemical entit...
متن کاملDevelopment and Validation of Spectrofluorometric, Spectrophotometric and Thin Layer Chromatography Stability Indicating Methods for Analysis of Topiramate
Three selective, inexpensive and validated methods were developed and optimized for determination of antiepileptic drug, topiramate in drug substance and drug product as well as in the presence of its acid, base and thermal degradants. The first method is micelle-enhanced spectrofluorimetric assay based on the reaction between the studied drug and fluorescamine to give highly fluorescent deriva...
متن کاملDevelopment and Validation of High Performance Thin Layer
A simple, specific and precise high performance thin layer chromatographic method was developed and validated for estimation of Brimonidine tartrate as bulk drug and in ophthalmic solutions. The chromatographic development was carried out on precoated silica gel 60 F254 aluminium plates using mixture of Methanol: Ammonia (8:0.2 v/v) as mobile phase and densitometric evaluation of band was carri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asian Journal of Chemistry
سال: 2017
ISSN: 0970-7077,0975-427X
DOI: 10.14233/ajchem.2017.20661